Research Associate, Comparative Medicine/Pathology Associate
- B.A./B.S. or equivalent in a biological science with a minimum 1-2 years of experience in a laboratory animal research setting preferred
- Will accept new grads with lab experience (internship, co-op, etc.)
- Basic proficient with basic laboratory rodent procedures is a must
- Perform basic histology procedures to prepare samples for analysis (trimming, processing, embedding, microtomy, staining, and cover slipping) independently or under the direction of certified histotechnologists.Comparative Medicine/Pathology
We are seeking a laboratory animal technician with proficiency in performing basic in-life procedures and necropsies in laboratory rodents, as well as basic processing techniques for fluid and tissue samples. This unique role will also involve ex vivo sample processing in collaboration with Pathologists and Histotechnologists. The incumbent will have a track record of working collaboratively across functions and strong technical skills in laboratory rodents. The role will serve to enable biopharmaceutical research into new therapeutic candidates by assisting with animal model characterization, obtaining safety and efficacy readouts following treatment, and helping to determine the mechanism of action of potential new treatments. The role will be based in the Comparative Medicine department but will have an expectation of approximately 50% time working collaboratively with the Pathology department to provide end-to-end support for studies in laboratory rodents. While the research facility is not an official Good Laboratory Practices (GLP) compliant facility, all studies are performed in GLP-like fashion with attention to data integrity and thorough documentation.
- Independently perform basic necropsy procedures in laboratory rodents (dissection, tissue collection and trimming, sample collection, etc.) as well as specialized techniques such as perfusion fixation and specialized dissections under the direction of board-certified veterinary pathologists.
- Independently collect and process terminal blood samples; collect and process other terminal fluid samples under the direction of a veterinarian or senior scientist
- The incumbent may perform the above duties alongside research scientists; must be prepared to work collaboratively and be flexible, depending on the timelines, readouts, and specific circumstances of a given animal study
- Perform basic histology procedures to prepare samples for analysis (trimming, processing, embedding, microtomy, staining, and cover slipping) independently or under the direction of certified histotechnologists
- Perform ex vivo processing of fluid samples to support clinical pathology
- Provide oversight of necropsy rooms within the vivarium to include:
Equipment calibration, certification, and maintenance Stock consumables Ensure compliance with Environmental Health & Safety guidelines for hazardous substances in the necropsy room Ensure biosecurity and protection of personnel from hazards, and Ensure all small and large equipment is in good working order and replaced when necessary
- Assist with data acquisition & entry, including report preparation of data collected during necropsy; provide study directors with proper documentation of any protocol deviations involving necropsy, sample collection, or ex vivo processing
- Review SOPs related to necropsy and tissue collection/processing, work with Environmental Health & Safety and Occupational Health to ensure safe work practices and policies in the necropsy rooms, assist with necropsy room audits and safety inspections
- Bachelor’s degree (B.A./B.S.) or equivalent in a biological science with a minimum 1 year of experience in a laboratory animal research setting preferred.
- An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
- Proven track record of collaborative work practices
- Ability to be flexible and communicate effectively
- Willing to learn new techniques
- Basic proficient with basic laboratory rodent procedures
- Familiarity with various types of data acquisition and protocol management software, as well as Microsoft Office applications, is strongly desired.