Search Jobs

Filter
Project Engineer (2)
*2* Product Coordinators (1)
*2* Supply Chain Resources (1)
*3* Order Management Resources (1)
A/P Supervisor  (1)
Account Executive (PERM) (1)
Accountant I - 8829709 & 8829729 (1)
Applications Manager (PERM) (1)
Associate Project Manager/ Project Manager I - 9005449 (1)
Associate Technical Lead, Software Development (Temp-To-Perm) (1)
Azure Developer - R1010039.01 (1)
Bioinformatics Analyst (1)
CD Operations Engineer - 8838556 (1)
Change Management Consultant - R1010061.01 (1)
Change Manager Consultant - R1010060.01 (1)
Clinical Data Manager - 8884540 (1)
Coding Quality Coordinator (1)
Coding Specialist (1)
Collections Specialist (1)
Communication Specialist, IT 8856935 (1)
Construction Supervisor (1)
Contract Recruiter (1)
Contracts Paralegal - 8899109 (1)
Control System Support Specicalist (PERM) (1)
Controller (1)
Controls Engineer (1)
CRM Service Consultant (1)
Data Analyst, Business Intelligence (Temp-to-Perm) (1)
Data Architect, Insight Services (Temp-to-Perm) (1)
Data Intelligence Analyst (Temp-to-Perm) (1)
Director of Product Management, Cloud Services (PERM) (1)
EH&S Manager - 8907392 (1)
Electrical Design Engineer (X3) (1)
Electrical Engineer (PERM) (1)
Embedded Software Design Engineer (1)
Estimator (1)
Executive Assistant III - 9010484 (1)
Field Service Engineer (PERM) (1)
Financial Analyst - 8722454 (1)
HR Coordinator (1)
HR Learning & Development Project Coordinator - 8795069 (1)
Instrument & Controls Technician (1)
Integration Analyst (Temp-To-Perm) (1)
IT Support Engineer - Brockton (1)
Knowledge Management Specialist – Customer Care - 9006440 (1)
Manager, Clinical Data Management - 8882215 (1)
Manufacturing Engineer (1)
Manufacturing Engineer - EE (1)
Marketing Specialist - 8796030 (1)
Partner Solutions Engineer (PERM) (1)
Payroll & HRIS Coordinator (PERM) (1)
Planner (1)
Planning Associate (1)
Principal Digital Marketing Expert - Paid Media Strategy (1)
Principal Software Engineer, Cloud Platform & Infrastructure (PERM) (1)
Procurement Specialist 2 (1)
Product Manager (1)
Production Supervisor (1)
QA Engineer ME (1)
QC Associate II (Preclinical) (1)
Quality Engineer I (PERM) (1)
Quality Engineering Manager I (PERM) (1)
Report Developer II, Business Intelligence (Temp-to-Perm) (1)
Retail MDM Architect - R1010010.01 (1)
Sales Account Executive (PERM) (1)
Sales Recruiter - 8873673 (1)
Sales Sourcer - 8900230 (1)
SAP PI Developer - R1010059.01 (1)
Scientist - Hydraulic (PERM) (1)
Scrum Master (PERM) (1)
Senior Accountant (1)
Senior Applications Analyst (PERM) (1)
Senior Architect, Software Development (Temp-to-Perm) (1)
Senior Coding Analyst (1)
Senior Maintenance Electrician (1)
Senior QA Engineer- San Diego, CA (1)
Senior Salesforce CPQ Analyst (PERM) (1)
Senior Software Developer/Vision Engineer (1)
Senior Software Engineer, Sustaining (PERM) (1)
Senior Technician, Materials Processing (PERM) (1)
Senior U/X Designer, Mobile (PERM) (1)
Senior/Principal Software Engineer (PERM) (1)
Service Desk Technician - 9006556 (1)
SOA Developer (porting Android to iOS) - R1010012.01 (1)
Software Engineer II (PERM) (1)
Software Engineer in Test - 9007198 (1)
Software Engineer IV - PLC - Leesburg,VA (1)
Software Engineer, Development Engineering (1)
Solutions Architect (PERM) (1)
SQL Server BI report Developer (1)
Sr. BIM Design Engineer (1)
Sr. HelpDesk Analyst (1)
Sr. Mechanical Engineer (1)
Sr. Paralegal - 8892877 (1)
Sr. Software Developer (Fullstack) - 8815812 (1)
Sr. Software Test Technician (2 openings) - 8891749 (1)
Supervisor Talent Acquisition Operations (1)
Technical Writer (1)
Technical Writer - 8861096 (1)
Technical Writer, GxP Digital Quality Systems (1)
Upstream Principal Scientist-MS&T - 8907358 (1)
User Interface Developer IV - 8889897 (1)
Validation Engineer (2 openings) - 8892329 (1)
Warehouse Manager (1)
Web Business Analyst/Content Expert - 8915555 (1)
Windows Device Driver Developer (1)
Windows Systems/Citrix Xenapp Administrator - R1010062.01 (1)
Share:
« Return to Jobs
9557
Contract

Upstream Principal Scientist-MS&T - 8907358

Location: Emeryville, California

Connexion Systems & Engineering, a Boston based IT and Engineering Solutions Company immediately seeks individuals with the following skills:

 

Date Posted: 2/7/2019

Hiring Organization: Connexion Systems & Engineering

Job Title: Upstream Principal Scientist – MS&T

Industry: Manufacturing/Medical

Location: Emeryville, CA

Employment Type: Full Time, Contract

Pay Range: Open

Duration: 1 Year

Job#:bh9557

 

Upstream Principal Scientist -MS&T - Manufacturing Sciences and Technology

Successful candidate will provide technical or scientific expertise & leadership in the upstream process development of mammalian cell culture derived recombinant proteins & monoclonal antibodies.

In addition to upstream process development candidate will lead efforts for developing & optimizing cell culture processes including process parameter optimization, process characterization & scale-up/tech transfer for large scale product production.

Candidate will also have experience with microbial fermentation-based processes & associated process development, technical transfer & support successful implementation of production fermentation processes at commercial scale.

Has considerable knowledge in area of protein & monoclonal antibodies production using mammalian host cell systems, experience with microbial based host cell systems for recombinant protein production is a plus.

Responsible for design & execution of experiments regarding cell culture media screening/development, evaluate feeding strategies, process parameter optimization & scale-up to support large scale production

Candidate will monitor, explore & evaluate next generation technologies to speed up process development.

Be responsible for technology transfer to third parties including partners & CMO Supports process technology transfer & scale-up to commercial facilities Individual will be accountable for scientific data review including data integrity verification, statistical analysis & technical report writing.

Directly interfaces with other departmental groups (R&D, Quality Assurance, Regulatory Affairs, Supply Chain & Manufacturing)

Skills:

Technical/scientific knowledge of biopharmaceutical processes, both process development & manufacturing scales of operation

Knowledge of process scale-up & scale-down methodologies, including process characterization & design of experiments

Understanding/experience with wave bag systems & SUBs is essential.

Familiarity with Finesse Delta V control systems & PI systems is highly desirable.

Experience in process technology transfer within & between organizations, manufacturing support & troubleshooting

Demonstrated teamwork, organizational & leadership skills

Writes procedures & technical reports that include data interpretation.

Extensive working knowledge of cGMP environments

Attention to detail, strong organizational skills, ability to multitask, effective interpersonal & communication skills are required.

Can identify & request needed resources within or across functional areas.

Must have advanced written & oral communication skills.

Independently applies sound scientific principles in development of innovative solutions to complex technical problems.

Skilled in application of standardized root cause analysis, investigation tools & methodologies.

Proficient with the use of MS Office (Excel, Word, PowerPoint), application software including Unicorn, JMP, Minitab, Design Expert, etc.

Keywords:

Education: Master's or PhD in science or engineering preferred

Minimum of 10 yrs. experience in product development, manufacturing science & technology, process engineering within the pharmaceutical industry required

7 yrs. experience working in a pharmaceutical manufacturing site

Familiarization with global regulations on drugs, medical devices, combination products or validation / qualification requirements

Skills and Experience:

Required Skills:

BIOPHARMACEUTICAL

CGMP

CONTROL SYSTEMS

DATA INTEGRITY

DELTA V

Additional Skills:

FERMENTATION

JMP

LEADERSHIP SKILLS

MEDICAL DEVICES

MINITAB

OPTIMIZATION

ORGANIZATIONAL SKILLS

PHARMACEUTICAL MANUFACTURING

PROBLEM SOLVING

PROCESS DEVELOPMENT

PROCESS ENGINEERING

PRODUCT DEVELOPMENT

QUALITY ASSURANCE

REGULATORY AFFAIRS

REPORT WRITING

ROOT CAUSE ANALYSIS

STATISTICAL ANALYSIS

SUPPLY CHAIN

TECHNICAL LEADERSHIP

TECHNICAL REPORT WRITING

ANTIBODIES

APPLICATION SOFTWARE

CELL CULTURE

EXCEL

MAMMALIAN CELL CULTURE

MICROSOFT EXCEL

MICROSOFT OFFICE

MICROSOFT POWERPOINT

MICROSOFT WORD

MONOCLONAL

MS OFFICE

POWERPOINT

WORD

 

 

When responding to this job posting you MUST include the Job# and Job Title in your subject line.

                 

Contact Info:                                                                                                                                             

 

ConneXion Systems & Engineering

490 Boston Post Road

Sudbury, MA 01776

jobpostings@csetalent.com